Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246159 | 0.81 | TP53 (0.56) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL21994509 | 0.78 | LMNA (0.36) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL21994656 | 0.78 | LMNA (0.39) | TP53LMNAHTTTSHRCYP3A4 | |
| SCHEMBL21994510 | 0.78 | MAPK1 (0.33) | TP53LMNAHTTTSHRALDH1A1 | |
| SCHEMBL20680189 | 0.78 | TP53 (0.48) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL4995477 | 0.77 | TP53 (0.63) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL15440744 | 0.75 | TP53 (0.60) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL29700271 | 0.73 | TP53 (0.58) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL7560420 | 0.73 | TP53 (0.58) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL21995126 | 0.72 | SLC6A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887362-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109391-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | WO | disclosed |