Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | ABL2 | P42684 | 1/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199558 | 1.00 | FBP1 (0.67) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL27957137 | 0.82 | FBP1 (0.69) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL27946453 | 0.82 | FBP1 (0.69) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL2746679 | 0.82 | FBP1 (0.69) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL2746675 | 0.82 | FBP1 (0.69) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL10664676 | 0.82 | FBP1 (0.69) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL2746676 | 0.82 | FBP1 (0.69) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL6469695 | 0.81 | FBP1 (0.67) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL1245803 | 0.81 | FBP1 (0.67) | FBP1LMNAMAPTMEN1KMT2A | |
| SCHEMBL107299 | 0.81 | FBP1 (0.67) | FBP1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115746692-A | Low dielectric coating and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-115403983-A | Sun-proof heat-preservation coating for vehicles and preparation method thereof | 夏敏 | 2022-11-29 | — | — | CN | claimed |
| EP-2982368-A1 | Small molecule compounds displacing focal adhesion core components | Universität Konstanz (DE) | 2016-02-10 | — | — | EP | claimed |
| US-11912721-B2 | Fused pentacyclic imidazole derivatives | UCB Biopharma SRL (BE) | 2024-02-27 | — | — | US | disclosed |
| CN-115746692-B | Low dielectric coating and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115746692-B | Low dielectric coating and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111825656-B | Inhibitors of protein arginine methyltransferase 5 (PRMT 5), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115746692-A | Low dielectric coating and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115746692-A | Low dielectric coating and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| US-11591326-B2 | Inhibitors of protein arginine methyltransferase 5 (PRMT5), pharmaceutical products thereof, and methods thereof | PHARMABLOCK SCIENCES (NANJING), INC. (CN) | 2023-02-28 | — | — | US | disclosed |
| CN-115403983-A | Sun-proof heat-preservation coating for vehicles and preparation method thereof | 夏敏 | 2022-11-29 | — | — | CN | disclosed |
| US-6521605-B1 | Potentiating glutamate receptor function; treating such as psychiatric and neurological disorders | ELI LILLY AND COMPANY | 2003-02-18 | — | — | US | disclosed |
| US-20020002158-A1 | Sulphonamide derivatives | ARNOLD MACKLIN B (US) | 2002-01-03 | — | — | US | disclosed |
| US-6303816-B1 | Sulphonamide derivatives | ELI LILLY AND COMPANY | 2001-10-16 | — | — | US | disclosed |
| WO-2000006537-A1 | N-SUBSTITUTED SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006176-A1 | AMIDOPHOSPHATE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006156-A1 | AMIDE, CARBAMATE, AND UREA DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976744-A1 | Amide, carbamate, and urea derivatives having glutamate receptor function potentiating activity | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0860428-A2 | Sulphonamide derivatives | ELI LILLY AND COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1998033496-A1 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002158-A1 | Sulphonamide derivatives | GRIN2C, GRM1, GRM3 | FBP1 1690/4885LMNA 2852/4885MAPT 4777/4885 |
| US-11591326-B2 | Inhibitors of protein arginine methyltransferase 5 (PRMT5), pharmaceutical products thereof, and methods thereof | PRMT5, PRMT1, PRMT3 | FBP1 3981/4885LMNA 3766/4885MAPT 3510/4885 |
| US-11912721-B2 | Fused pentacyclic imidazole derivatives | TNF, NFKBIA, TNFRSF1A | FBP1 734/4885LMNA 2126/4885MAPT 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.