SCHEMBL2199579

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2195814	0.91	AVPR2 (0.64)	MAPK13MAPK12MAPK11MAPK14AVPR2
	SCHEMBL2198282	0.91	MAPK14 (0.60)	MAPK13MAPK12MAPK11MAPK14AVPR2
	SCHEMBL2203090	0.89	MAPK13 (0.59)	MAPK13MAPK12MAPK11MAPK14AVPR2
	SCHEMBL2196799	0.88	MAPK14 (0.49)	MAPK13MAPK12MAPK11MAPK14AVPR2
	SCHEMBL2199428	0.87	MAPK14 (0.60)	MAPK13MAPK12MAPK11MAPK14MAPT
	SCHEMBL2199707	0.87	MAPK14 (0.54)	MAPK13MAPK12MAPK11MAPK14AVPR2
	SCHEMBL2199713	0.86	MAPK14 (0.54)	MAPK13MAPK12MAPK11MAPK14AVPR2
	SCHEMBL2200544	0.86	ALDH1A1 (0.50)	MAPK13MAPK12MAPK11MAPK14TSHR
	SCHEMBL2198654	0.85	MAPK14 (0.57)	MAPK13MAPK12MAPK11MAPK14AVPR2
	SCHEMBL2199687	0.85	MAPK13 (0.53)	MAPK13MAPK12MAPK11MAPK14MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.