Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859623 | 0.86 | ALDH1A1 (0.51) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL9689634 | 0.83 | KDM4E (0.53) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL2759541 | 0.81 | ALDH1A1 (0.53) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL24348727 | 0.79 | DPP4 (0.63) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL20138279 | 0.79 | KDM4E (0.51) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL859998 | 0.79 | KDM4E (0.65) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL13348090 | 0.77 | KDM4E (0.45) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL13220757 | 0.77 | KMT2A (0.51) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL10517025 | 0.75 | ALDH1A1 (0.48) | KMT2AKDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL16156201 | 0.75 | KMT2A (0.58) | KMT2AKDM4EALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886848-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | Rutgers, The State University of New Jersey (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020112845-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-06-04 | — | — | WO | disclosed |