Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996534 | 0.89 | ABCB1 (0.41) | BACE1BACE2CARM1PRMT6DDB1 | |
| SCHEMBL21996612 | 0.86 | USP30 (0.34) | BACE1BACE2DDB1CRBNGPR119 | |
| SCHEMBL24622151 | 0.86 | BACE1 (0.39) | BACE1BACE2CARM1PRMT6NAAA | |
| SCHEMBL22047122 | 0.86 | HDAC4 (0.40) | BACE1BACE2CARM1PRMT6NAAA | |
| SCHEMBL21996313 | 0.86 | BACE1 (0.39) | BACE1BACE2CARM1PRMT6NAAA | |
| SCHEMBL21996651 | 0.85 | BACE1 (0.38) | BACE1BACE2CARM1PRMT6NAAA | |
| SCHEMBL24622085 | 0.81 | BACE1 (0.36) | BACE1BACE2CARM1PRMT6NAAA | |
| SCHEMBL16434872 | 0.79 | BACE1 (0.49) | BACE1BACE2CARM1PRMT6NAAA | |
| SCHEMBL7107445 | 0.75 | RORC (0.41) | BACE1BACE2CARM1PRMT6DDB1 | |
| SCHEMBL6770180 | 0.75 | RORC (0.41) | BACE1BACE2CARM1PRMT6DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113077-A9 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020113077-A1 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-06-04 | — | — | WO | disclosed |