Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748473 | 0.82 | MAPK1 (0.46) | MAPK1KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL16321938 | 0.79 | CYP2C9 (0.38) | MAPK1KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL5844244 | 0.77 | CRHR1 (0.40) | HTR6MAPK1KDM4ELMNAHSD17B10 | |
| SCHEMBL17926536 | 0.76 | MAPK1 (0.48) | MAPK1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL1748597 | 0.74 | MAPK1 (0.35) | MAPK1KDM4ELMNAHTTHSD17B10 | |
| Hydrochloric Acid SCHEMBL1748596 | 0.73 | MAPK1 (0.34) | MAPK1KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL5844147 | 0.73 | MAPK1 (0.46) | MAPK1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL12482022 | 0.73 | MAPT (0.48) | MAPK1KDM4ELMNAHTTMAPT | |
| SCHEMBL21996632 | 0.72 | GAA (0.40) | SMN1; SMN2TDP1GAA | |
| SCHEMBL1055154 | 0.71 | MAPK1 (0.53) | MAPK1KDM4ELMNAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251104-A1 | AROMATIC COMPOUNDS FOR USE IN ACTIVATING HEMATOPOIETIC STEM AND PROGENITOR CELLS | CELULARITY INC. (US) | 2022-08-11 | — | — | US | disclosed |
| EP-3887364-A1 | AROMATIC COMPOUNDS FOR USE IN ACTIVATING HEMATOPOIETIC STEM AND PROGENITOR CELLS | Celularity Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| CN-113454076-A | Aromatic compounds for activating hematopoietic stem and progenitor cells | 细胞结构公司 | 2021-09-28 | — | — | CN | disclosed |
| WO-2020113178-A1 | AROMATIC COMPOUNDS FOR USE IN ACTIVATING HEMATOPOIETIC STEM AND PROGENITOR CELLS | Celularity, Inc. (US) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251104-A1 | AROMATIC COMPOUNDS FOR USE IN ACTIVATING HEMATOPOIETIC STEM AND PROGENITOR CELLS | ALPP, MCL1, NFATC1 | HTR6 528/4885MAPK1 2857/4885KDM4E 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.