SCHEMBL2199674

SCHEMBL2199674

c1csc(N=Nc2nccs2)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.55
KMT2A Q03164 6/20 0.55
MEN1 O00255 5/20 0.55
KDM4E B2RXH2 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
POLB P06746 2/20 0.55
MAPK1 P28482 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
IDO1 P14902 1/20 0.55
TDO2 P48775 1/20 0.55
GFER P55789 1/20 0.55
HSP90AA1 P07900 2/20 0.52
CCR6 P51684 1/20 0.52
RAB9A P51151 2/20 0.49
PAX8 Q06710 1/20 0.49
KCNH2 Q12809 1/20 0.49
RIOK2 Q9BVS4 1/20 0.49
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31085482 0.85
SCHEMBL15116312 0.85
SCHEMBL31085484 0.85
SCHEMBL1305761 0.82 KMT2A (0.50) MAPTKMT2AMEN1KDM4EL3MBTL1
SCHEMBL1305759 0.82 KMT2A (0.50) MAPTKMT2AMEN1KDM4EL3MBTL1
SCHEMBL4299916 0.82 ALDH1A1 (0.46) MAPTKMT2AMEN1KDM4EL3MBTL1
SCHEMBL9747992 0.81 MAPT (0.46) MAPTKMT2AMEN1KDM4EL3MBTL1
SCHEMBL12071015 0.79 MAPT (0.45) MAPTKMT2AMEN1KDM4EL3MBTL1
SCHEMBL12669309 0.79 MEN1 (0.61) MAPTKMT2AMEN1KDM4EL3MBTL1
SCHEMBL9324602 0.79 MAPT (0.52) MAPTKMT2AMEN1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3672643-A2 MAGNETIC RESONANCE TOMOGRAPHY CONTRAST MEDIA, USE THEREOF FOR MEASURING TEMPERATURE AND METHOD FOR MEASURING TEMPERATURE Christian-Albrechts-Universität zu Kiel (DE) 2020-07-01 EP claimed
CN-106062163-A Long alkyl chain azo dyes and laundry detergent compositions 荷兰联合利华有限公司 2016-10-26 CN claimed
CN-104379718-A Liquid laundry detergent UNILEVER NV 2015-02-25 CN claimed
CN-102482623-A Method for neutralizing the color of a composition PROCTER & GAMBLE 2012-05-30 CN claimed
CN-100503595-C Second-order nonlinear optical polymer containing azo and thiophene ring and synthetic method and application thereof CHINESE ACAD TECH INST PHYSICS (CN) 2009-06-24 CN claimed
CN-1814595-A Second-order nonlinear optical polymer containing azo and thiophene ring and synthetic method and application thereof PHYSICAL CHEMICAL TECHNOLOGY I (CN) 2006-08-09 CN claimed
EP-0216957-A1 Cyan dye-releasing compounds for use in the production of diffusion transfer colour images AGFA-GEVAERT N.V. (BE) 1987-04-08 EP claimed
CN-113337139-B Thiazole azo dye and synthetic method thereof 天津全和诚科技有限责任公司 2023-02-28 CN disclosed
CN-113337139-A Thiazole azo dye and synthetic method thereof 天津全和诚科技有限责任公司 2021-09-03 CN disclosed
EP-3672643-A2 MAGNETIC RESONANCE TOMOGRAPHY CONTRAST MEDIA, USE THEREOF FOR MEASURING TEMPERATURE AND METHOD FOR MEASURING TEMPERATURE Christian-Albrechts-Universität zu Kiel (DE) 2020-07-01 EP disclosed
CN-110475546-A Physiological activator carrier LEMONEX INC 2019-11-19 CN disclosed
CN-110088261-A Cleaning compositions comprising enzyme 宝洁公司 2019-08-02 CN disclosed
CN-110023476-A Cleaning compositions comprising enzymes 宝洁公司 2019-07-16 CN disclosed
US-20060048673-A1 SOLUBILIZED DYES FOR INKS EASTMAN KODAK COMPANY 2006-03-09 US disclosed
CN-1130485-C Dyed filament yarn exhibiting vivid color TEIJIN LTD (JP) 2003-12-10 CN disclosed
US-20030199523-A1 Heterocyclic calcium in channel blockers ZALICUS PHARMACEUTICALS LTD. (CA) 2003-10-23 US disclosed
CN-1208445-A Dyed filament yarn having clear hue TEIJIN LTD (JP) 1999-02-17 CN disclosed
CN-1128278-A Azothiophene dyes containing a 2,4,6-triamino-3-cyanopyridine coupling component CIBA GEIGY AG (CH) 1996-08-07 CN disclosed
EP-0216957-A1 Cyan dye-releasing compounds for use in the production of diffusion transfer colour images AGFA-GEVAERT N.V. (BE) 1987-04-08 EP disclosed
EP-0216957-A1 Cyan dye-releasing compounds for use in the production of diffusion transfer colour images AGFA-GEVAERT N.V. (BE) 1987-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199523-A1 Heterocyclic calcium in channel blockers CACNA1C, CACNA1B, CACNA1D MAPT 1537/4885KMT2A 4239/4885MEN1 1836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.