SCHEMBL9324602

SCHEMBL9324602

Nc1ccc(/N=N/c2nccs2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.52
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
L3MBTL1 Q9Y468 5/20 0.52
RAB9A P51151 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
NPC1 O15118 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
HTT P42858 2/20 0.45
PKM P14618 1/20 0.45
KDM4E B2RXH2 4/20 0.45
POLB P06746 2/20 0.45
MAPK1 P28482 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
IDO1 P14902 1/20 0.45
TDO2 P48775 1/20 0.45
GFER P55789 1/20 0.45
HSP90AA1 P07900 2/20 0.43
CCR6 P51684 1/20 0.43
FBP1 P09467 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6553922 1.00 MAPT (0.52) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL12071722 0.82 L3MBTL1 (0.49) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL12071015 0.81 MAPT (0.45) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL8669445 0.81 MEN1 (0.61) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL12669309 0.81 MEN1 (0.61) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL1305759 0.81 KMT2A (0.50) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL1305761 0.81 KMT2A (0.50) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL2199674 0.79 MAPT (0.55) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL12070993 0.78 L3MBTL1 (0.48) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL4809460 0.77 MAOA (0.51) MAPTMEN1KMT2AL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2580289-B1 BLACK DICHROIC DYE BASF SE (DE) 2017-11-29 EP disclosed
US-9057020-B2 Black dichroic dye BASF SE (DE) 2015-06-16 US disclosed
US-9057020-B2 Black dichroic dye BASF SE (DE) 2015-06-16 US disclosed
US-20130092874-A1 BLACK DICHROIC DYE BASF SE (DE) 2013-04-18 US disclosed
US-20130092874-A1 BLACK DICHROIC DYE BASF SE (DE) 2013-04-18 US disclosed
WO-2011157614-A1 BLACK DICHROIC DYE BASF SE (DE) 2011-12-22 WO disclosed
EP-0432563-B1 4-Substituted-5-chloro-2-hydrazino thiazols BAYER AG (DE) 1994-03-09 EP disclosed
US-5068343-A Fungicides for plants BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
EP-0432563-A2 4-Substituted-5-chloro-2-hydrazino thiazols BAYER AG (DE) 1991-06-19 EP disclosed