SCHEMBL219972

SCHEMBL219972

C=C[C@@]1(C)CC(=O)[C@]2(O)[C@@]3(C)[C@@H](O)CCC(C)(C)[C@@H]3[C@H](OC(=O)CCN(C)C)[C@H](OC(C)=O)[C@@]2(C)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 1.00
CYP3A4 P08684 4/20 1.00
TSHR P16473 3/20 1.00
NR1I2 O75469 2/20 1.00
ADRA1A P35348 2/20 1.00
CYP2C19 P33261 2/20 1.00
KMT2A Q03164 2/20 1.00
MLNR O43193 1/20 1.00
KCNH2 Q12809 1/20 1.00
MEN1 O00255 1/20 1.00
ALDH1A1 P00352 1/20 1.00
CYP2C9 P11712 1/20 1.00
ADCY1 Q08828 13/20 0.79
SLC2A1 P11166 2/20 0.72
GMNN O75496 1/20 0.72
BLM P54132 1/20 0.72
PMP22 Q01453 1/20 0.72
NPSR1 Q6W5P4 1/20 0.72
CYP2D6 P10635 1/20 0.72
NFKB1 P19838 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20034151 1.00 MAPK1 (1.00) MAPK1CYP3A4TSHRNR1I2ADRA1A
SCHEMBL23659154 1.00 MAPK1 (1.00) MAPK1CYP3A4TSHRNR1I2ADRA1A
SCHEMBL29397687 1.00 MAPK1 (1.00) MAPK1CYP3A4TSHRNR1I2ADRA1A
Hydrochloric Acid SCHEMBL2230892 0.99 MAPK1 (0.98) MAPK1CYP3A4TSHRNR1I2ADRA1A
Hydrochloric Acid SCHEMBL1651080 0.98 MAPK1 (0.97) MAPK1CYP3A4TSHRNR1I2ADRA1A
SCHEMBL2233173 0.93 MAPK1 (0.86) MAPK1CYP3A4TSHRNR1I2ADRA1A
SCHEMBL7296382 0.91 MAPK1 (0.84) MAPK1CYP3A4TSHRNR1I2ADRA1A
SCHEMBL7298484 0.91 MAPK1 (0.84) MAPK1CYP3A4TSHRNR1I2ADRA1A
SCHEMBL16181423 0.91 MAPK1 (0.83) MAPK1CYP3A4TSHRNR1I2ADRA1A
SCHEMBL7295088 0.90 MAPK1 (0.82) MAPK1CYP3A4TSHRNR1I2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083698-A1 Synergistic Stimulation of Mucociliary Clearance to Treat Mucus Obstruction in Cystic Fibrosis and Other Muco-Obstructive Disorders UNIV LELAND STANFORD JUNIOR (US) 2026-03-26 US claimed
EP-3831933-B1 METHOD FOR PRODUCING INTESTINAL EPITHELIAL CELLS AND INTESTINAL EPITHELIAL CELLS FUJIFILM CORP (JP) 2025-10-29 EP claimed
US-20250263669-A1 INDUCED TOTIPOTENT STEM CELLS AND PREPARATION METHOD THEREFOR UNIV TSINGHUA (CN) 2025-08-21 US claimed
US-20250064859-A1 HPSC-DERIVED ARTICULAR CHONDROCYTE COMPOSITIONS, SYSTEMS AND METHODS OF USE THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2025-02-27 US claimed
EP-4493679-A1 HPSC-DERIVED ARTICULAR CHONDROCYTE COMPOSITIONS, SYSTEMS AND METHODS OF USE THEREOF The Children's Medical Center Corporation (US) 2025-01-22 EP claimed
WO-2024233640-A1 COMPOSITIONS AND METHODS FOR INHIBITING SEIZURES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-14 WO claimed
EP-4394030-A1 INDUCED TOTIPOTENT STEM CELLS AND PREPARATION METHOD THEREFOR Tsinghua University (CN) 2024-07-03 EP claimed
WO-2024064151-A1 SYNERGISTIC STIMULATION OF MUCOCILIARY CLEARANCE TO TREAT MUCUS OBSTRUCTION IN CYSTIC FIBROSIS AND OTHER MUCO-OBSTRUCTIVE DISORDERS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-03-28 WO claimed
WO-2023196234-A1 METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES GLAZIER ALAN NEIL (US) 2023-10-12 WO claimed
WO-2023196235-A1 METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES GLAZIER ALAN NEIL (US) 2023-10-12 WO claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-6919076-B1 Conjugates of agents and transglutaminase substrate linking molecules PERICOR SCIENCE, INC. (US) 2005-07-19 US claimed
EP-1539930-A2 MULTI-STEP METHOD FOR THE DIFFERENTIATION OF INSULIN POSITIVE, GLUCOSE ES Cell International Pte Ltd. (SG) 2005-06-15 EP claimed
US-20040110287-A1 Multi-step method for the differentiation of insulin positive, glucose responsive cells ES CELL INTERNATIONAL PTE LTD. 2004-06-10 US claimed
WO-2004011621-A2 MULTI-STEP METHOD FOR THE DIFFERENTIATION OF INSULIN POSITIVE, GLUCOSE ES CELL INTERNATIONAL PTE LTD. (SG) 2004-02-05 WO claimed
US-6475525-B1 Oral preparations containing forskolin derivatives and process for producing pharmaceutical preparations NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2002-11-05 US claimed
EP-1094781-A1 COMPOSITIONS FOR RAPID AND NON-IRRITATING TRANSDERMAL DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS AND METHODS FOR FORMULATING SUCH COMPOSITIONS AND DELIVERY THEREOF Transdermal Technologies Inc. (US) 2001-05-02 EP claimed
CN-1292692-A Oral preparations containing forskolin derivatives and process for producing medicinal preparations NIPPON KAYAKU KK (JP) 2001-04-25 CN claimed
EP-1074253-A1 ORAL PREPARATIONS CONTAINING FORSKOLIN DERIVATIVES AND PROCESS FOR PRODUCING MEDICINAL PREPARATIONS Nippon Kayaku Kabushiki Kaisha (JP) 2001-02-07 EP claimed
WO-2000001351-A1 COMPOSITIONS FOR RAPID AND NON-IRRITATING TRANSDERMAL DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS AND METHODS FOR FORMULATING SUCH COMPOSITIONS AND DELIVERY THEREOF TRANSDERMAL TECHNOLOGIES, INC. (US) 2000-01-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083698-A1 Synergistic Stimulation of Mucociliary Clearance to Treat Mucus Obstruction in Cystic Fibrosis and Other Muco-Obstructive Disorders CFTR, ADRB2, ADRA1D MAPK1 2814/4885CYP3A4 2938/4885TSHR 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.