SCHEMBL2199810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2199605	0.84	PARP1 (0.47)	CDC7BRD4IKBKBJAK2JAK3
	SCHEMBL2200000	0.84	IKBKB (0.51)	CDC7BRD4IKBKBJAK2JAK3
	SCHEMBL2198095	0.84	CDC7 (0.57)	CDC7BRD4CSF1RFLT1
	SCHEMBL2200146	0.84	BRD4 (0.62)	CDC7BRD4IKBKBJAK2JAK3
	SCHEMBL12509786	0.83	BRD4 (0.44)	CDC7BRD4IKBKBJAK2JAK3
	SCHEMBL2199237	0.83	CDC7 (0.56)	CDC7BRD4IKBKBJAK2JAK3
	SCHEMBL2196883	0.83	CDC7 (0.56)	CDC7BRD4IKBKBJAK2JAK3
	SCHEMBL2196489	0.83	IKBKB (0.52)	BRD4IKBKBJAK2JAK3PARP1
	SCHEMBL2198955	0.83	CDC7 (0.59)	CDC7BRD4IKBKBJAK2PARP1
	SCHEMBL4348768	0.83	IKBKB (0.46)	CDC7BRD4IKBKBJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.