Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770951 | 0.80 | USP2 (0.48) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL6871920 | 0.79 | ALDH1A1 (0.53) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL14459791 | 0.78 | ALDH1A1 (0.47) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL25338490 | 0.77 | MEN1 (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5402831 | 0.77 | ALDH1A1 (0.46) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL8211734 | 0.74 | LMNA (0.57) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL27451626 | 0.74 | USP2 (0.43) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL27182185 | 0.73 | USP2 (0.37) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL23086623 | 0.73 | CYP4F2 (0.33) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL15140431 | 0.71 | CYP2D6 (0.30) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886904-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020113233-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |