Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.36 |
| ▸ | CPB1 | P15086 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL8066127 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1RXFP1CPB2CPB1 | |
| Purine SCHEMBL5788025 | 0.90 | SLC7A5 (0.42) | SMN1; SMN2ALDH1A1RXFP1CPB2CPB1 | |
| Purine SCHEMBL28177652 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1RXFP1CPB2CPB1 | |
| Purine SCHEMBL28724547 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1RXFP1CPB2CPB1 | |
| Purine SCHEMBL9934578 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1RXFP1CYP1A2NTRK1 | |
| Purine SCHEMBL29465224 | 0.84 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1RXFP1CYP1A2CYP3A4 | |
| Purine SCHEMBL27414327 | 0.84 | ALDH1A1 (0.43) | ALDH1A1RXFP1NTRK1KDM4ETSHR | |
| Purine SCHEMBL28153340 | 0.84 | KDM4E (0.39) | SMN1; SMN2ALDH1A1RXFP1CYP1A2NTRK1 | |
| Purine SCHEMBL28164598 | 0.83 | ALDH1A1 (0.44) | ALDH1A1RXFP1CYP1A2CYP3A4KDM4E | |
| Aspartic Acid SCHEMBL28172600 | 0.83 | CYP3A4 (0.41) | SMN1; SMN2ALDH1A1RXFP1CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083737-A | A kind of miazines alanine derivatives that can be used for oncotherapy and its preparation method and application | 河南师范大学 | 2016-11-09 | — | — | CN | claimed |
| CN-106083856-A | A kind of purines alanine derivatives that can be used for oncotherapy and its preparation method and application | 河南师范大学 | 2016-11-09 | — | — | CN | claimed |
| US-20220024999-A1 | METHODS OF MODULATING RNA | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2022-01-27 | — | — | US | disclosed |
| EP-3887516-A1 | METHODS OF MODULATING RNA | Flagship Pioneering Innovations V, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| CN-113454216-A | Methods of modulating RNA | 旗舰先锋创新V股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| WO-2020113135-A1 | METHODS OF MODULATING RNA | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| CN-106074557-B | D type guanine alanine is preparing the application in medicines resistant to liver cancer | 河南师范大学 | 2019-07-05 | — | — | CN | disclosed |
| CN-107686505-A | A kind of new tripeptide compound for containing 1 willardin and its preparation method and application | 河南师范大学 | 2018-02-13 | — | — | CN | disclosed |
| CN-107365352-A | A kind of new tripeptide compound for containing 9 adenine alanine and its preparation method and application | 河南师范大学 | 2017-11-21 | — | — | CN | disclosed |
| CN-106083856-A | A kind of purines alanine derivatives that can be used for oncotherapy and its preparation method and application | 河南师范大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-106083856-A | A kind of purines alanine derivatives that can be used for oncotherapy and its preparation method and application | 河南师范大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-106083856-A | A kind of purines alanine derivatives that can be used for oncotherapy and its preparation method and application | 河南师范大学 | 2016-11-09 | — | — | CN | disclosed |