Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21994164 | 0.92 | KMT2A (0.43) | TRPV1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL10176295 | 0.82 | KMT2A (0.47) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL13753685 | 0.78 | CA1 (0.64) | TRPV1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL15199080 | 0.77 | ALDH1A1 (0.56) | TRPV1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8955019 | 0.76 | CNR2 (0.50) | CNR1CNR2 | |
| SCHEMBL23731657 | 0.74 | SMN1; SMN2 (0.45) | TRPV1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL21726734 | 0.74 | KMT2A (0.53) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL13865093 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL3277623 | 0.73 | TRPV1 (0.58) | TRPV1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL25005768 | 0.73 | KIF11 (0.47) | ALDH1A1LMNAMAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941160-B2 | Bromodomain inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200148703-A1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941160-B2 | Bromodomain inhibitors | BRD3, EP300, BRPF3 | TRPV1 4620/4885ALDH1A1 3316/4885KMT2A 77/4885 |
| US-20200148703-A1 | BROMODOMAIN INHIBITORS | BRD3, EP300, BRPF3 | TRPV1 4620/4885ALDH1A1 3316/4885KMT2A 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.