Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996658 | 0.98 | NPC1 (0.56) | NPC1KDM4EALDH1A1RAB9AMAOB | |
| SCHEMBL21998494 | 0.95 | NPC1 (0.55) | NPC1KDM4EALDH1A1RAB9AMAOB | |
| SCHEMBL21994192 | 0.83 | NPC1 (0.68) | NPC1KDM4EALDH1A1RAB9AMAOB | |
| SCHEMBL21933265 | 0.82 | MAPT (0.59) | NPC1KDM4EALDH1A1RAB9AKMT2A | |
| SCHEMBL21994189 | 0.81 | NPC1 (0.72) | NPC1KDM4EALDH1A1RAB9AMAOB | |
| SCHEMBL21994187 | 0.80 | MEN1 (0.52) | NPC1KDM4EALDH1A1RAB9AKMT2A | |
| SCHEMBL21998502 | 0.80 | MAPT (0.49) | NPC1KDM4EALDH1A1RAB9AMAOB | |
| SCHEMBL21998480 | 0.79 | EPHX2 (0.70) | NPC1KDM4EALDH1A1RAB9ATRPM8 | |
| SCHEMBL21933276 | 0.78 | EPHX2 (0.65) | NPC1KDM4EALDH1A1RAB9AMAOB | |
| SCHEMBL21994188 | 0.78 | RAB9A (0.61) | NPC1KDM4EALDH1A1RAB9ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | STS, F12, GLB1 | NPC1 1617/4885KDM4E 4389/4885ALDH1A1 449/4885 |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | STS, F12, STK38L | NPC1 1139/4885KDM4E 4442/4885ALDH1A1 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.