Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21994189 | 0.97 | NPC1 (0.72) | NPC1EPHX2KDM4EMAPTRAB9A | |
| SCHEMBL21933276 | 0.95 | EPHX2 (0.65) | NPC1EPHX2KDM4EMAPTRAB9A | |
| SCHEMBL21994191 | 0.87 | EPHX2 (0.60) | NPC1EPHX2KDM4EMAPTRAB9A | |
| SCHEMBL21998496 | 0.83 | NPC1 (0.53) | NPC1EPHX2KDM4EMAPTRAB9A | |
| SCHEMBL21994190 | 0.83 | ALDH1A1 (0.61) | NPC1EPHX2KDM4EMAPTRAB9A | |
| SCHEMBL21996658 | 0.81 | NPC1 (0.56) | NPC1EPHX2KDM4EMAPTRAB9A | |
| SCHEMBL21933245 | 0.80 | KDM4E (0.81) | NPC1EPHX2KDM4EMAPTRAB9A | |
| SCHEMBL5025132 | 0.80 | NPC1 (0.86) | NPC1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL21998497 | 0.78 | EPHX2 (0.67) | NPC1EPHX2KDM4EMAPTRAB9A | |
| SCHEMBL19097940 | 0.78 | EPHX2 (0.70) | NPC1EPHX2KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | STS, F12, GLB1 | NPC1 1617/4885EPHX2 3414/4885KDM4E 4389/4885 |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | STS, F12, STK38L | NPC1 1139/4885EPHX2 3354/4885KDM4E 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.