Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799134 | 0.77 | PTGS2 (0.39) | IDH1TYRALDH1A1ALOX12HTT | |
| SCHEMBL11317932 | 0.75 | PTGS2 (0.49) | IDH1TYRALDH1A1ALOX12HTT | |
| SCHEMBL26007774 | 0.72 | PTGS2 (0.46) | IDH1TYRALDH1A1ALOX12HTT | |
| SCHEMBL21959664 | 0.72 | IDH1 (0.37) | IDH1TYRALDH1A1ALOX12HTT | |
| SCHEMBL889379 | 0.72 | MGLL (0.48) | TYRALDH1A1HTTRNASEH1KDM4E | |
| SCHEMBL14501877 | 0.72 | ACACB (0.40) | IDH1TYRALDH1A1ALOX12HTT | |
| SCHEMBL26005499 | 0.72 | PTGS2 (0.68) | IDH1TYRALDH1A1ALOX12HTT | |
| SCHEMBL26005494 | 0.72 | PTGS2 (0.54) | IDH1TYRALDH1A1ALOX12HTT | |
| SCHEMBL15468864 | 0.71 | PTGS2 (0.39) | IDH1TYRALDH1A1ALOX12HTT | |
| SCHEMBL15469125 | 0.71 | HDAC6 (0.45) | IDH1ALDH1A1KDM4EMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11638764-B2 | Theranostic capture agents, compositions, and methods of using and making | INDI MOLECULAR, INC. (US) | 2023-05-02 | — | — | US | disclosed |
| US-11638764-B2 | Theranostic capture agents, compositions, and methods of using and making | INDI MOLECULAR, INC. (US) | 2023-05-02 | — | — | US | disclosed |
| US-20200147244-A1 | THERANOSTIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING | INDI MOLECULAR, INC. | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11638764-B2 | Theranostic capture agents, compositions, and methods of using and making | PSMA1, FOLH1, PSMA6 | IDH1 1172/4885TYR 1614/4885ALDH1A1 2009/4885 |
| US-20200147244-A1 | THERANOSTIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING | PSMA1, FOLH1, PSMA6 | IDH1 1172/4885TYR 1614/4885ALDH1A1 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.