Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197728 | 0.88 | GAA (0.55) | CYP3A4ALDH1A1LMNAHTTMMP13 | |
| SCHEMBL2197758 | 0.82 | KDM4E (0.67) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL21246564 | 0.81 | RECQL (0.58) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| SCHEMBL29437185 | 0.81 | RECQL (0.58) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| SCHEMBL2198760 | 0.81 | MAPK13 (0.58) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| SCHEMBL29437175 | 0.79 | ALDH1A1 (0.63) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| SCHEMBL21222734 | 0.79 | ALDH1A1 (0.63) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| SCHEMBL2196637 | 0.78 | HPGD (0.51) | CYP1A2CYP3A4TSHRL3MBTL1LMNA | |
| SCHEMBL19623369 | 0.78 | ALDH1A1 (0.78) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| SCHEMBL10323918 | 0.77 | CYP1A2 (0.61) | CYP1A2CYP3A4TSHRBLML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | NFKBIA, UACA, ALDH7A1 | CYP1A2 517/4885CYP3A4 613/4885TSHR 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.