Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21931866 | 0.90 | TDP1 (0.35) | APPALDH1A1HSD17B1HSD17B2TSHR | |
| SCHEMBL21931871 | 0.87 | TSHR (0.34) | APPALDH1A1HSD17B1HSD17B2HPGD | |
| SCHEMBL21931872 | 0.82 | APP (0.34) | APPALDH1A1HSD17B1HSD17B2HPGD | |
| SCHEMBL13197643 | 0.77 | TSHR (0.43) | APPALDH1A1HSD17B1HSD17B2HPGD | |
| SCHEMBL13197642 | 0.77 | TSHR (0.46) | APPALDH1A1HSD17B1HSD17B2HPGD | |
| SCHEMBL13197616 | 0.76 | TSHR (0.42) | APPALDH1A1HSD17B1HSD17B2HPGD | |
| SCHEMBL13197653 | 0.76 | TSHR (0.44) | APPALDH1A1HSD17B1HSD17B2HPGD | |
| SCHEMBL13125840 | 0.75 | APP (0.54) | APPHSD17B1HSD17B2ALOX5RAB9A | |
| SCHEMBL10109359 | 0.74 | APP (0.56) | APPALDH1A1HSD17B1HSD17B2ALOX5 | |
| SCHEMBL17051482 | 0.74 | APP (0.56) | APPALDH1A1HSD17B1HSD17B2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200147078-A1 | THERANOSTIC AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147078-A1 | THERANOSTIC AGENTS | FAP, MKI67, PAIP1 | APP 613/4885ALDH1A1 1066/4885HSD17B1 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.