Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465752 | 0.93 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL22198349 | 0.85 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL10067025 | 0.83 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL19291834 | 0.83 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL8965481 | 0.83 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL19806252 | 0.80 | TSHR (0.40) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL20930887 | 0.80 | TSHR (0.38) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL15495149 | 0.80 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL22418021 | 0.79 | ALDH1A1 (0.43) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL22926219 | 0.79 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180601-B2 | Polyurethane dispersions | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200148806-A1 | POLYURETHANE DISPERSIONS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2020-05-14 | — | — | US | disclosed |