Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999396 | 0.93 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL8965481 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL22926219 | 0.85 | TSHR (0.60) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL81413 | 0.81 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL23494302 | 0.80 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL8966180 | 0.79 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL22475202 | 0.79 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL8965587 | 0.79 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL26661210 | 0.79 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL22475204 | 0.78 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990202-A | DURABLE, SMEAR-FAST INK FILMS COMPRISING DUAL ENCAPSULATED COLORANT; A PRIMER CORE/SHELL POLYMER COATING A COLORANT (ADHESION) AND AN EXTERIOR CORE/SHELL POLYMER COATING FOR DURABILITY | HEWLETT-PACKARD COMPANY (US) | 1999-11-23 | — | — | US | disclosed |