Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433374 | 0.85 | HSD17B10 (0.44) | ACLYHSD17B10HPGDALDH1A1ALOX15 | |
| SCHEMBL21999657 | 0.84 | ACLY (0.42) | ACLYHSD17B10HPGDALDH1A1ALOX15 | |
| SCHEMBL25210351 | 0.74 | CYP3A4 (0.35) | ALDH1A1ALOX15GAAKMT2AFABP3 | |
| SCHEMBL5318762 | 0.73 | CA1 (0.41) | ACLYHSD17B10HPGDALDH1A1ALOX15 | |
| SCHEMBL9349986 | 0.72 | CYP3A4 (0.37) | HSD17B10HPGDALDH1A1ALOX15GAA | |
| SCHEMBL10576669 | 0.72 | CA1 (0.34) | HSD17B10HPGDALOX15GAAFABP3 | |
| SCHEMBL28730405 | 0.72 | AHR (0.36) | HSD17B10HPGDALDH1A1ALOX15FABP3 | |
| SCHEMBL25828290 | 0.71 | HSD17B10 (0.48) | HSD17B10HPGDALDH1A1ALOX15GAA | |
| SCHEMBL20025716 | 0.71 | FABP3 (0.37) | HSD17B10HPGDALDH1A1ALOX15FABP3 | |
| SCHEMBL20025727 | 0.71 | FABP3 (0.37) | HSD17B10HPGDALDH1A1ALOX15FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | ACLY, ATP5ME, ATP5MG | ACLY 1/4885HSD17B10 392/4885HPGD 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.