Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242650 | 0.83 | RPS6KA3 (0.43) | MAPK1RPS6KA3HSD17B10ALDH1A1LMNA | |
| SCHEMBL4306555 | 0.82 | CES1 (0.43) | CYP3A4CES1CYP2C9HSD17B10ALDH1A1 | |
| SCHEMBL19206145 | 0.81 | CYP3A4 (0.41) | CYP3A4MAPK1CYP2C9HSD17B10ALDH1A1 | |
| SCHEMBL1955903 | 0.79 | CYP3A4 (0.50) | CYP3A4MAPK1CES1CYP2C9HSD17B10 | |
| SCHEMBL5189655 | 0.79 | TRPA1 (0.38) | CYP3A4MAPK1RPS6KA3HSD17B10ALDH1A1 | |
| SCHEMBL4991882 | 0.78 | ALDH1A1 (0.44) | CYP3A4CES1CYP2C9HSD17B10ALDH1A1 | |
| SCHEMBL8369083 | 0.78 | LMNA (0.40) | RPS6KA3HSD17B10ALDH1A1LMNATDP1 | |
| SCHEMBL17271962 | 0.76 | LMNA (0.39) | RPS6KA3HSD17B10ALDH1A1LMNATDP1 | |
| Ammonia Solution, Strong SCHEMBL17272327 | 0.76 | LMNA (0.39) | RPS6KA3HSD17B10ALDH1A1LMNATDP1 | |
| SCHEMBL17272132 | 0.76 | LMNA (0.39) | RPS6KA3HSD17B10ALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292932-A | Diazotization and reaction with mineral acid of a similar compound containing amine group in place of hydroxyl | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| EP-0486606-A1 | PROCESS FOR PREPARING 5-CHLOR-2-HYDROXY-4-ALKYL-BENZENE-SULPHONIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-27 | — | — | EP | disclosed |
| WO-1991002717-A1 | PROCESS FOR PREPARING 5-CHLOR-2-HYDROXY-4-ALKYL-BENZENE-SULPHONIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-07 | — | — | WO | disclosed |