SCHEMBL220010

SCHEMBL220010

C=CC(=O)Oc1cccc2c(O)cccc12

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.61
ESR2 Q92731 13/20 0.61
KMT2A Q03164 6/20 0.57
MEN1 O00255 5/20 0.57
GAA P10253 5/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
JAK2 O60674 1/20 0.57
USP2 O75604 1/20 0.57
MAPT P10636 1/20 0.57
ALOX15 P16050 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
HSD17B10 Q99714 1/20 0.57
POLB P06746 2/20 0.50
TYMS P04818 1/20 0.50
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
ALDH1A1 P00352 1/20 0.40
CDC25B P30305 1/20 0.37
CDK2 P24941 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1508109 0.91 TYMS (0.56) ESR1ESR2KMT2AMEN1GAA
SCHEMBL30342255 0.91 TYMS (0.56) ESR1ESR2KMT2AMEN1GAA
SCHEMBL824860 0.90 ESR1 (0.54) ESR1ESR2KMT2AMEN1GAA
SCHEMBL220008 0.85 ESR1 (0.49) ESR1ESR2KMT2AMEN1GAA
SCHEMBL8070515 0.84 HSD17B10 (0.45) ESR1ESR2KMT2AMEN1GAA
SCHEMBL31295365 0.84 HSD17B10 (0.45) ESR1ESR2KMT2AMEN1GAA
SCHEMBL10720203 0.83 TYMS (0.56) ESR1ESR2KMT2AMEN1GAA
SCHEMBL15447071 0.83 TYMS (0.58) ESR1ESR2KMT2AMEN1GAA
SCHEMBL218920 0.82 THRB (0.50) ESR1ESR2KMT2AMEN1GAA
SCHEMBL29497650 0.82 THRB (0.50) ESR1ESR2KMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2384457-B1 COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2022-07-06 EP disclosed
US-20190346763-A1 COMPOSITIONS COMPRISING HETERO-SUBSTITUTED CARBOCYCLIC ARYL COMPONENT AND PROCESSES FOR PHOTOLITHOGRAPHY ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2019-11-14 US disclosed
US-10359698-B2 Compositions comprising hetero-substituted carbocyclic aryl component and processes for photolithography ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2019-07-23 US disclosed
US-9869931-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-16 US disclosed
US-9869931-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-16 US disclosed
US-20170115565-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-27 US disclosed
US-20170115565-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-27 US disclosed
US-20170115566-A1 RESIST COMPOSITION, PATTERNING PROCESS, AND BARIUM, CESIUM AND CERIUM SALTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-27 US disclosed
US-20170115566-A1 RESIST COMPOSITION, PATTERNING PROCESS, AND BARIUM, CESIUM AND CERIUM SALTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-27 US disclosed
US-9551928-B2 Actinic-ray- or radiation-sensitive resin composition and method of forming pattern therewith FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-20080166636-A1 Polymer, Crosslinked Polymer, Composition for Solid Polymer Electrolyte, Solid Polymer Electrolyte, and Adhesive Composition NIPPON SODA CO., LTD. (JP) 2008-07-10 US disclosed
EP-1923418-A1 STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2008-05-21 EP disclosed
US-20080048149-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIC MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2008-02-28 US disclosed
US-20080048149-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIC MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2008-02-28 US disclosed
EP-1873228-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIC MATERIAL, OPTICAL ELEMENT, AND OPTICAL HEAD DEVICE Asahi Glass Company, Limited (JP) 2008-01-02 EP disclosed
EP-1847556-A1 POLYMER, CROSSLINKED POLYMER, COMPOSITION FOR SOLID POLYMER ELECTROLYTE, SOLID POLYMER ELECTROLYTE AND ADHESIVE COMPOSITION NIPPON SODA CO., LTD. (JP) 2007-10-24 EP disclosed
EP-1780224-A1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2007-05-02 EP disclosed
US-20070040145-A1 e.g.block copolymer of methoxypolyethylene glycol mono (meth)acrylate with monomers selected from unsaturated ether, alcohol, ester, nitrile, carboxy, anhydride etc.; excellent in thermal properties, physical properties and ion conductivity NIPPON SODA CO., LTD. (JP) 2007-02-22 US disclosed
US-20070040145-A1 e.g.block copolymer of methoxypolyethylene glycol mono (meth)acrylate with monomers selected from unsaturated ether, alcohol, ester, nitrile, carboxy, anhydride etc.; excellent in thermal properties, physical properties and ion conductivity NIPPON SODA CO., LTD. (JP) 2007-02-22 US disclosed
EP-1553117-B1 SOLID POLYMER ELECTROLYTE NIPPON SODA CO (JP) 2007-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170115566-A1 RESIST COMPOSITION, PATTERNING PROCESS, AND BARIUM, CESIUM AND CERIUM SALTS CASR, LIFR, LBR ESR1 818/4885ESR2 874/4885KMT2A 2108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.