SCHEMBL8070515

SCHEMBL8070515

C=CC(=O)Oc1cccc(O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.45
HPGD P15428 4/20 0.45
THRB P10828 4/20 0.45
ALOX15 P16050 3/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPT P10636 3/20 0.45
KDM4E B2RXH2 3/20 0.45
LMNA P02545 2/20 0.45
THRA P10827 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX12 P18054 1/20 0.45
MAPK1 P28482 1/20 0.45
TYMS P04818 1/20 0.43
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CDK2 P24941 2/20 0.41
ADAMTS4 O75173 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31295365 1.00 HSD17B10 (0.45) HSD17B10HPGDTHRBALOX15ALDH1A1
SCHEMBL4751279 0.87 THRB (0.44) HSD17B10HPGDTHRBALOX15ALDH1A1
SCHEMBL29497650 0.86 THRB (0.50) HSD17B10HPGDTHRBALOX15ALDH1A1
SCHEMBL218920 0.86 THRB (0.50) HSD17B10HPGDTHRBALOX15ALDH1A1
SCHEMBL8355220 0.85 TYMS (0.40) THRBTHRATYMS
SCHEMBL5147452 0.84 THRB (0.46) HSD17B10HPGDTHRBALOX15ALDH1A1
SCHEMBL220010 0.84 ESR1 (0.61) HSD17B10THRBALOX15ALDH1A1MAPT
SCHEMBL28900006 0.84 THRB (0.42) HSD17B10HPGDTHRBALOX15ALDH1A1
SCHEMBL21314234 0.82 KDM4E (0.53) HSD17B10HPGDTHRBALOX15ALDH1A1
SCHEMBL29413361 0.81 THRB (0.56) HSD17B10HPGDTHRBALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0756204-B1 Photopolymerizable composition and photosensitive lithographic printing plate employing it MITSUBISHI CHEM CORP (JP) 2000-09-20 EP disclosed
US-5837422-A ON A SUSTRATE CONTATINING ADDITION POLYMERIZABLE UNSATURATED BONDS WITH AND WITHOUT URETHANE BONDS; HIGH SENSITIVITY TO LIGNT IN VISIBLE REGION AND EXCELLENT DEVELOPABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 1998-11-17 US disclosed
EP-0756204-A1 Photopolymerizable composition and photosensitive lithographic printing plate employing it MITSUBISHI CHEMICAL CORPORATION (JP) 1997-01-29 EP disclosed
EP-0213440-B1 POLYMERIZABLE COMPOUNDS AND METHOD FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-19 EP disclosed
EP-0212439-B1 POLYMERS AND RADIOSENSITIVE COMPOSITIONS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-16 EP disclosed
US-4910119-A Blend of acrylated ester, unsaturated compound and photoinitiator HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-20 US disclosed
US-4739097-A Monoacrylates of trihydric phenols and method for producing same HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-19 US disclosed
EP-0213440-A2 Polymerizable compounds and method for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-11 EP disclosed
EP-0212439-A2 Polymers and radiosensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed
US-4554346-A REACTION WITH UNSATURATED HYDROXY COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-11-19 US disclosed