Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | MAOB | P27338 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA3 | P07451 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937064 | 1.00 | ALDH1A1 (0.70) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL13538681 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL28719031 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL28719029 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL22001514 | 0.84 | ALDH1A1 (0.72) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL28715500 | 0.84 | CYP2C19 (0.68) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL28715502 | 0.84 | CYP2C19 (0.68) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL1104931 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL28713651 | 0.82 | KDM4E (0.64) | ALDH1A1HPGDMAOBKDM4EHSD17B10 | |
| SCHEMBL28715499 | 0.82 | KDM4E (0.64) | ALDH1A1HPGDMAOBKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283180-B | Method for synthesizing pyridine [3,4-c ] coumarin | 长沙理工大学 | 2022-03-29 | — | — | CN | claimed |
| CN-110283180-B | Method for synthesizing pyridine [3,4-c ] coumarin | 长沙理工大学 | 2022-03-29 | — | — | CN | disclosed |
| US-11142511-B2 | Coumarin oxime ester compounds, preparation and use thereof | HUBEI GURUN TECHNOLOGY CO., LTD. (CN) | 2021-10-12 | — | — | US | disclosed |
| EP-3660008-A1 | COUMARIN OXIME ESTER COMPOUND AND PREPARATION AND USE THEREOF | Hubei Gurun Technology Co., Ltd (CN) | 2020-06-03 | — | — | EP | disclosed |
| US-20200148660-A1 | COUMARIN OXIME ESTER COMPOUNDS, PREPARATION AND USE THEREOF | HUBEI GURUN TECHNOLOGY CO. LTD (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148660-A1 | COUMARIN OXIME ESTER COMPOUNDS, PREPARATION AND USE THEREOF | CBR3, POR, CYP3A4 | ALDH1A1 457/4885HPGD 400/4885MAOB 660/4885 |
| US-11142511-B2 | Coumarin oxime ester compounds, preparation and use thereof | CBR3, POR, CYP3A4 | ALDH1A1 457/4885HPGD 400/4885MAOB 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.