Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MAOB | P27338 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719029 | 1.00 | ALDH1A1 (0.64) | ALDH1A1MAOBHPGDGAAKDM4E | |
| SCHEMBL28715502 | 0.91 | CYP2C19 (0.68) | ALDH1A1MAOBHPGDGAAKDM4E | |
| SCHEMBL28715500 | 0.91 | CYP2C19 (0.68) | ALDH1A1MAOBHPGDGAAKDM4E | |
| SCHEMBL28937064 | 0.86 | ALDH1A1 (0.70) | ALDH1A1MAOBHPGDGAAKDM4E | |
| SCHEMBL22001389 | 0.86 | ALDH1A1 (0.70) | ALDH1A1MAOBHPGDGAAKDM4E | |
| SCHEMBL13538681 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAOBHPGDGAAKDM4E | |
| SCHEMBL28705253 | 0.83 | KDM4E (0.58) | ALDH1A1MAOBHPGDKDM4ECA12 | |
| SCHEMBL28705252 | 0.83 | KDM4E (0.58) | ALDH1A1MAOBHPGDKDM4ECA12 | |
| SCHEMBL23871953 | 0.80 | CYP2C19 (0.81) | ALDH1A1MAOBHPGDGAAKDM4E | |
| SCHEMBL22001552 | 0.80 | HSD11B1 (0.43) | ALDH1A1MAOBHPGDGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283180-B | Method for synthesizing pyridine [3,4-c ] coumarin | 长沙理工大学 | 2022-03-29 | — | — | CN | claimed |
| CN-110283180-B | Method for synthesizing pyridine [3,4-c ] coumarin | 长沙理工大学 | 2022-03-29 | — | — | CN | disclosed |