Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 4/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997534 | 0.87 | MMP13 (0.41) | PDPK1KLKB1CHRM1NTRK1BRD4 | |
| SCHEMBL21043088 | 0.83 | CHRM1 (0.60) | CHRM1 | |
| SCHEMBL16593235 | 0.83 | CHRM1 (0.60) | CHRM1 | |
| SCHEMBL21043062 | 0.77 | NNMT (0.42) | KLKB1CHRM1ENPP2CYP11B1CSF1R | |
| SCHEMBL22001379 | 0.75 | LOX (0.42) | PDPK1 | |
| SCHEMBL16593223 | 0.73 | CHRM1 (0.59) | CHRM1 | |
| SCHEMBL18616106 | 0.72 | BRD4 (0.48) | PDPK1BRD4 | |
| SCHEMBL16593239 | 0.71 | CHRM1 (0.59) | CHRM1 | |
| SCHEMBL16593324 | 0.71 | CHRM1 (0.74) | CHRM1 | |
| SCHEMBL16593350 | 0.71 | CHRM1 (0.58) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-B1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2020-05-13 | — | — | EP | disclosed |