Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | CCR1 | P32246 | 3/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.60 |
| ▸ | CCR8 | P51685 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202808 | 1.00 | KDM4E (0.77) | KDM4EL3MBTL1LMNATP53CCR1 | |
| SCHEMBL14549596 | 0.88 | KDM4E (1.00) | KDM4EL3MBTL1LMNATP53CCR1 | |
| SCHEMBL2201113 | 0.79 | GP6 (0.59) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL14297276 | 0.78 | KDM4E (0.82) | KDM4EL3MBTL1LMNATP53CCR1 | |
| SCHEMBL14297310 | 0.78 | KDM4E (0.82) | KDM4EL3MBTL1LMNATP53CCR1 | |
| SCHEMBL12925670 | 0.78 | KDM4E (0.82) | KDM4EL3MBTL1LMNATP53CCR1 | |
| SCHEMBL994705 | 0.78 | KDM4E (0.82) | KDM4EL3MBTL1LMNATP53CCR1 | |
| SCHEMBL7964803 | 0.78 | KDM4E (1.00) | KDM4EL3MBTL1LMNATP53CCR1 | |
| Terpyridine SCHEMBL57442 | 0.78 | KDM4E (1.00) | KDM4EL3MBTL1LMNATP53CCR1 | |
| Terpyridine SCHEMBL29357603 | 0.78 | KDM4E (1.00) | KDM4EL3MBTL1LMNATP53CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385052-B1 | Compound having oxadiazole ring structure substituted with pyridyl group, and organic electroluminescent device | HODOGAYA CHEMICAL CO LTD (JP) | 2013-11-13 | — | — | EP | disclosed |
| EP-2385052-A1 | Compound having oxadiazole ring structure substituted with pyridyl group, and organic electroluminescent device | Hodogaya Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7977671-B2 | Compound having oxadiazole ring structure substituted with pyridyl group and organic electroluminescence device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7812341-B2 | Compound having oxadiazole ring structure substituted with pyridyl group, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20100066244-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP AND ORGANIC ELECTROLUMINESCENCE DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20080017846-A1 | Compound Having Oxadiazole Ring Structure Substituted with Pyridyl Group, and Organic Electroluminescent Device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1746094-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2007-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100066244-A1 | COMPOUND HAVING OXADIAZOLE RING STRUCTURE SUBSTITUTED WITH PYRIDYL GROUP AND ORGANIC ELECTROLUMINESCENCE DEVICE | OXA1L, LEF1, PNPO | KDM4E 608/4885L3MBTL1 2128/4885LMNA 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.