SCHEMBL22003182

SCHEMBL22003182

Cc1c(F)cc(I)c(C(F)(F)F)c1I

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.35
NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18252877 0.68 PDE2A (0.35)
SCHEMBL17468318 0.67
SCHEMBL3458958 0.67 NOTUM (0.34) SOS1NOTUM
SCHEMBL18428488 0.66 HDAC1 (0.31)
SCHEMBL18721405 0.66 HDAC1 (0.31)
SCHEMBL7929436 0.65 TTR (0.39) SOS1NOTUM
SCHEMBL14449318 0.65
SCHEMBL27501093 0.64 TTR (0.41) SOS1NOTUM
SCHEMBL26548110 0.64
SCHEMBL25037001 0.64 KIF11 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174115-B1 CHARGE TRANSPORT MATERIAL NISSAN CHEMICAL CORP (JP) 2020-05-20 EP disclosed