Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69776 | 0.74 | TTR (0.56) | TTRALBTDP1CHEK1DAPK3 | |
| SCHEMBL12817414 | 0.69 | TTR (0.50) | TTRALBTDP1CHEK1DAPK3 | |
| SCHEMBL6720850 | 0.69 | TTR (0.50) | TTRALBTDP1CHEK1DAPK3 | |
| SCHEMBL7930045 | 0.69 | TTR (0.50) | TTRALBTDP1CHEK1DAPK3 | |
| SCHEMBL5274194 | 0.69 | TTR (0.50) | TTRNOTUMALBCHEK1DAPK3 | |
| SCHEMBL27501093 | 0.67 | TTR (0.41) | TTRSOS1NOTUM | |
| SCHEMBL8410940 | 0.67 | TTR (0.48) | TTRALBTDP1CHEK1DAPK3 | |
| SCHEMBL26618522 | 0.67 | NOTUM (0.30) | NOTUM | |
| SCHEMBL22003182 | 0.65 | SOS1 (0.35) | SOS1NOTUM | |
| SCHEMBL7926711 | 0.64 | KIF11 (0.34) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707849-B1 | USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S L (ES) | 2001-12-19 | — | — | EP | disclosed |
| US-5620677-A | CONTRAST AGENTS IN DIAGNOSTIC RADIOLOGY | STERLING WINTHROP INC. (US) | 1997-04-15 | — | — | US | disclosed |
| US-5607660-A | X-RAY CONTRAST AGENTS FOR INTESTINES | STERLING WINTHROP INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5531979-A | X-RAY CONTRAST COMPOSITION | STERLING WINTHROP INC. (US) | 1996-07-02 | — | — | US | disclosed |
| US-5472682-A | Mixed with clays, anionic, nonionic, cationic, zwitterionic surfactants, excipients and water; used in diagnostic radiology | STERLING WINTHROP INC. (US) | 1995-12-05 | — | — | US | disclosed |
| US-5468466-A | Compositions of iodophenyl sulfonates for X-ray visualization of the gastrointestinal tract | STERLING WINTHROP, INC. (US) | 1995-11-21 | — | — | US | disclosed |
| US-5385722-A | X-ray radiology and computer tomography; uniform coating of the soft tissues; medical diagnosis | STERLING WINTHROP INC. (US) | 1995-01-31 | — | — | US | disclosed |
| US-5372800-A | X-ray contrast coating | STERLING WINTHROP INC. (US) | 1994-12-13 | — | — | US | disclosed |
| EP-0617969-A2 | Compositions of iodophenyl esters and iodophenyl sulfonates for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-10-05 | — | — | EP | disclosed |
| EP-0617970-A2 | Compositions of iodophenyl esters and iodophenyl sulfonates in film-forming materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-10-05 | — | — | EP | disclosed |
| EP-0609586-A2 | Compositions of iodophenoxy alkanes and iodophenyl ethers for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-08-10 | — | — | EP | disclosed |
| EP-0609587-A2 | Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract | NYCOMED IMAGING AS (NO) | 1994-08-10 | — | — | EP | disclosed |
| US-5336484-A | Contrast compound comprising an iodobenzene ester and a Group 2A metal salt of a carboxylated or sulfonated polysaccharide in a carrier; uniform coating; radiology | STERLING WINTHROP INC. (US) | 1994-08-09 | — | — | US | disclosed |
| US-5326553-A | Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract | STERLING WINTHROP INC. (US) | 1994-07-05 | — | — | US | disclosed |
| US-5318769-A | Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract | STERLING WINTHROP INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5316755-A | AQUEOUS X-RAY CONTRAST COMPOSITION FOR ORAL OR RECTAL ADMINISTRATION | STERLING WINTHROP INC. (US) | 1994-05-31 | — | — | US | disclosed |