Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22003121 | 0.81 | EGLN1 (0.43) | HIF1AEGLN1TDP1ALDH1A1 | |
| SCHEMBL3415752 | 0.74 | HIF1A (0.45) | HIF1AEGLN1BBOX1ASPHKDM8 | |
| SCHEMBL3419484 | 0.67 | HSD17B10 (0.38) | TAAR1CYP2C9P2RX3RECQLHSD17B10 | |
| SCHEMBL14342749 | 0.65 | TAAR1 (0.44) | TAAR1CYP2C9FFAR1HSD17B10ALDH1A1 | |
| SCHEMBL24005735 | 0.61 | EGLN1 (0.46) | CYP2C9EGLN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL21129210 | 0.60 | ENPP2 (0.57) | EGLN1BBOX1ASPHKDM8ALDH1A1 | |
| SCHEMBL19267141 | 0.60 | TAAR1 (0.32) | TAAR1CYP2C9FFAR1ALDH1A1GPR119 | |
| SCHEMBL21129642 | 0.58 | HIF1A (0.38) | HIF1AEGLN1BBOX1ASPHKDM8 | |
| SCHEMBL24005450 | 0.58 | LIPG (0.39) | EGLN1 | |
| SCHEMBL25954462 | 0.58 | EGLN1 (0.46) | EGLN1BBOX1ASPHKDM8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157055-A1 | Prolyl Hydroxylase Inhibitors | GLAXOSMITHKLINE LLC (US) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157055-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN3, EGLN2 | HIF1A 4/4885TAAR1 3871/4885CYP2C9 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.