⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17267130 | 0.83 | — | — | |
| SCHEMBL28267107 | 0.77 | — | — | |
| SCHEMBL25892699 | 0.77 | — | — | |
| SCHEMBL16571102 | 0.73 | OPRM1 (0.35) | — | |
| SCHEMBL23335852 | 0.71 | — | — | |
| SCHEMBL21482253 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL436203 | 0.71 | — | — | |
| SCHEMBL2954654 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL1559355 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL1559358 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11229709-B2 | Dendrimer drug conjugates for sustained intra-articular delivery | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-01-25 | — | — | US | disclosed |
| US-20200155692-A1 | DENDRIMER DRUG CONJUGATES FOR SUSTAINED INTRA-ARTICULAR DELIVERY | UNITED STATES GOVERNMENT | 2020-05-21 | — | — | US | disclosed |