SCHEMBL436203

SCHEMBL436203

CCCC(N)SC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23335852 1.00
SCHEMBL11160083 0.80
SCHEMBL16571102 0.78 OPRM1 (0.35)
SCHEMBL785343 0.73
SCHEMBL28854334 0.73
SCHEMBL27989886 0.73
SCHEMBL11247559 0.73
SCHEMBL12743473 0.71
SCHEMBL22003302 0.71
SCHEMBL17267130 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118179206-A High desorption CO for flue gas2Absorbent agent 中国石油天然气股份有限公司 2024-06-14 CN disclosed
EP-2854861-A1 METHOD OF SYNTHESISING SULFORAPHANE Pharmagra Labs, Inc. (US) 2015-04-08 EP disclosed
WO-2013179057-A1 METHOD OF SYNTHESISING SULFORAPHANE PHARMAGRA LABS, INC. (US) 2013-12-05 WO disclosed
US-20130142739-A1 PROCESS FOR THE SYNTHESIS OF ISOTHIOCYANATES AND DERIVATIVES THEREOF AND USES OF SAME AURIGA INTERNATIONAL (BE) 2013-06-06 US disclosed
EP-2595953-A1 PROCESS FOR THE SYNTHESIS OF ISOTHIOCYANATES AND DERIVATIVES THEREOF AND USES OF SAME Auriga International (BE) 2013-05-29 EP disclosed
WO-2012010644-A1 PROCESS FOR THE SYNTHESIS OF ISOTHIOCYANATES AND DERIVATIVES THEREOF AND USES OF SAME AURIGA INTERNATIONAL (BE) 2012-01-26 WO disclosed
WO-2008015315-A1 THIOUREA-CONTAINING MEDICINAL COMPOUNDS FOR TREATING CANCER IN ASSOCIATION WITH CHEMOTHERAPUTIC AGENTS OR IONIZING OR NON-IONIZING RADIATION LMD (FR) 2008-02-07 WO disclosed
EP-1553933-B1 MEDICINE COMPRISING A THIOUREA FOR USE AS DEPIGMENTING AGENT OR ANTI-MUTAGENIC AND ANTI-CARCINOGENIC AGENT LMD (FR) 2007-07-25 EP disclosed
US-20060135618-A1 Medicine comprising a thiourea for use as depigmenting agent or anti-mutagenic and anti-carcinogenic agent LMD (FR) 2006-06-22 US disclosed
EP-1553933-A1 MEDICINE COMPRISING A THIOUREA FOR USE AS DEPIGMENTING AGENT OR ANTI-MUTAGENIC AND ANTI-CARCINOGENIC AGENT LMD (FR) 2005-07-20 EP disclosed
WO-2004032912-A1 MEDICINE COMPRISING A THIOUREA FOR USE AS DEPIGMENTING AGENT OR ANTI-MUTAGENIC AND ANTI-CARCINOGENIC AGENT LMD (FR) 2004-04-22 WO disclosed
US-20040077715-A1 Tyrosinase inhibitors; aging resistance; cosmetics LMD (FR) 2004-04-22 US disclosed
EP-1353644-A1 USE OF AN ISOTHIOCYANATE, A THIOCYANATE OR A MIXTURE THEREOF AS DEPIGMENTING AGENT Lmd (FR) 2003-10-22 EP disclosed
WO-2002058664-A1 USE OF AN ISOTHIOCYANATE, A THIOCYANATE OR A MIXTURE THEREOF AS DEPIGMENTING AGENT LMD (FR) 2002-08-01 WO disclosed
WO-2000025789-A1 A METHOD OF TREATING ENDOMETRIOSIS MERCK & CO., INC. (US) 2000-05-11 WO disclosed