Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14281850 | 1.00 | MEN1 (0.43) | MEN1KMT2AKDM4ENPSR1ALDH1A1 | |
| SCHEMBL13720968 | 0.86 | ESR1 (0.45) | POLBAPAF1LMNA | |
| SCHEMBL14599046 | 0.86 | ESR1 (0.45) | POLBAPAF1LMNA | |
| SCHEMBL1816436 | 0.85 | ALDH1A1 (0.50) | NPSR1ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL2393457 | 0.85 | ACACB (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17265776 | 0.85 | ACACB (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL12003862 | 0.85 | ALDH1A1 (0.50) | NPSR1ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL14445760 | 0.85 | POLB (0.54) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6809830 | 0.84 | APAF1 (0.57) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2408159 | 0.84 | APAF1 (0.57) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900278-B1 | RADIOPHARMACEUTICAL PRODUCTS FOR DIAGNOSIS AND THERAPY OF ADRENAL CARCINOMA | UNIV WUERZBURG J MAXIMILIANS (DE) | 2020-05-20 | — | — | EP | disclosed |