Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPLP1 | P05386 | 1/20 | 0.39 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.39 |
| ▸ | RPS17 | P08708 | 1/20 | 0.39 |
| ▸ | RPSA | P08865 | 1/20 | 0.39 |
| ▸ | RPS2 | P15880 | 1/20 | 0.39 |
| ▸ | RPL35A | P18077 | 1/20 | 0.39 |
| ▸ | RPL7 | P18124 | 1/20 | 0.39 |
| ▸ | RPL17 | P18621 | 1/20 | 0.39 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.39 |
| ▸ | RPS3 | P23396 | 1/20 | 0.39 |
| ▸ | RPS12 | P25398 | 1/20 | 0.39 |
| ▸ | RPL13 | P26373 | 1/20 | 0.39 |
| ▸ | RPL10 | P27635 | 1/20 | 0.39 |
| ▸ | RPL12 | P30050 | 1/20 | 0.39 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.39 |
| ▸ | RPL22 | P35268 | 1/20 | 0.39 |
| ▸ | RPL4 | P36578 | 1/20 | 0.39 |
| ▸ | RPS19 | P39019 | 1/20 | 0.39 |
| ▸ | RPL3 | P39023 | 1/20 | 0.39 |
| ▸ | RPL13A | P40429 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22005063 | 0.80 | HTR2A (0.40) | HTR2AHTR2C | |
| SCHEMBL22005019 | 0.72 | CHEK1 (0.42) | HTR2AHTR2C | |
| SCHEMBL22004977 | 0.71 | JAK2 (0.42) | JAK2JAK1JAK3BTKHTR2A | |
| SCHEMBL22004995 | 0.71 | CDK9 (0.41) | KCNH2CDK9 | |
| SCHEMBL29850569 | 0.70 | CHRM1 (0.40) | — | |
| SCHEMBL22004877 | 0.69 | CHEK1 (0.41) | — | |
| SCHEMBL19275554 | 0.68 | HTR2A (0.50) | HTR2AHTR2CHTR2B | |
| SCHEMBL11223267 | 0.68 | HTR6 (0.47) | HTR2A | |
| SCHEMBL22005425 | 0.68 | RPLP1 (0.38) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL22004740 | 0.68 | CHEK1 (0.43) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157092-A1 | [1,2,4]-TRIAZOLO [1,5-A]-PYRIMIDINYL DERIVATIVES SUBSTITUTED WITH PIPERIDINE, MORPHOLINE OR PIPERAZINE AS OGA INHIBITORS | Janssen Pharmaceutlca NV (BE) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157092-A1 | [1,2,4]-TRIAZOLO [1,5-A]-PYRIMIDINYL DERIVATIVES SUBSTITUTED WITH PIPERIDINE, MORPHOLINE OR PIPERAZINE AS OGA INHIBITORS | OGA, PSEN1, PSEN2 | RPLP1 1769/4885RPLP0 3247/4885RPS17 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.