Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.47 |
| ▸ | DRD3 | P35462 | 10/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930304 | 0.90 | DRD2 (0.48) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL7933893 | 0.87 | DRD2 (0.44) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL7879068 | 0.85 | DRD2 (0.46) | DRD2DRD3DRD4 | |
| SCHEMBL21255686 | 0.82 | DRD2 (0.39) | DRD2DRD3DRD4 | |
| SCHEMBL7533056 | 0.82 | DRD2 (0.44) | DRD2DRD3DRD4DRD1 | |
| SCHEMBL7533054 | 0.82 | DRD2 (0.44) | DRD2DRD3DRD4DRD1 | |
| SCHEMBL7336693 | 0.81 | DRD2 (0.47) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL7342658 | 0.81 | DRD2 (0.47) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL7336689 | 0.81 | DRD2 (0.47) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL7342652 | 0.81 | DRD2 (0.47) | DRD2DRD3DRD4HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653210-A1 | TREATMENT OF DYSKINESIA RELATED DISORDERS | H. Lundbeck A/S (DK) | 2020-05-20 | — | — | EP | disclosed |