Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 1.00 |
| ▸ | DRD1 | P21728 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50393 | 1.00 | DRD2 (1.00) | DRD2DRD1HTR1AMEN1LMNA | |
| SCHEMBL50391 | 1.00 | DRD2 (1.00) | DRD2DRD1HTR1AMEN1LMNA | |
| SCHEMBL50392 | 1.00 | DRD2 (1.00) | DRD2DRD1HTR1AMEN1LMNA | |
| SCHEMBL10034501 | 1.00 | DRD2 (1.00) | DRD2DRD1HTR1AMEN1LMNA | |
| SCHEMBL50689 | 1.00 | DRD2 (1.00) | DRD2DRD1HTR1AMEN1LMNA | |
| SCHEMBL10034502 | 1.00 | DRD2 (1.00) | DRD2DRD1HTR1AMEN1LMNA | |
| SCHEMBL51683 | 1.00 | DRD2 (1.00) | DRD2DRD1HTR1AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL50839 | 0.99 | DRD2 (0.98) | DRD2DRD1HTR1AMEN1LMNA | |
| SCHEMBL242083 | 0.91 | DRD2 (0.83) | DRD2DRD1HTR1A | |
| SCHEMBL50824 | 0.91 | DRD2 (0.83) | DRD2DRD1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653210-A1 | TREATMENT OF DYSKINESIA RELATED DISORDERS | H. Lundbeck A/S (DK) | 2020-05-20 | — | — | EP | disclosed |