Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.83 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50824 | 1.00 | DRD2 (0.83) | DRD2DRD1MTNR1BMTNR1AHTR1A | |
| Hydrochloric Acid SCHEMBL49920 | 0.99 | DRD2 (0.81) | DRD2DRD1MTNR1BMTNR1A | |
| SCHEMBL10034502 | 0.91 | DRD2 (1.00) | DRD2DRD1HTR1A | |
| SCHEMBL22005280 | 0.91 | DRD2 (1.00) | DRD2DRD1HTR1A | |
| SCHEMBL51683 | 0.91 | DRD2 (1.00) | DRD2DRD1HTR1A | |
| SCHEMBL10034501 | 0.91 | DRD2 (1.00) | DRD2DRD1HTR1A | |
| SCHEMBL50393 | 0.91 | DRD2 (1.00) | DRD2DRD1HTR1A | |
| SCHEMBL50689 | 0.91 | DRD2 (1.00) | DRD2DRD1HTR1A | |
| SCHEMBL50391 | 0.91 | DRD2 (1.00) | DRD2DRD1HTR1A | |
| SCHEMBL50392 | 0.91 | DRD2 (1.00) | DRD2DRD1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401255-A1 | CATECHOLAMINE DERIVATIVES AND PRODRUGS THEREOF | H. Lundbeck A/S (DK) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097087-A1 | CATECHOLAMINE DERIVATIVES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2010-09-02 | — | — | WO | disclosed |