Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720076 | 0.80 | IDO1 (0.45) | ALDH1A1KMT2ALMNAL3MBTL1TSHR | |
| SCHEMBL22005648 | 0.78 | TDP1 (0.53) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL27574000 | 0.76 | JAK2 (0.43) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL2705870 | 0.76 | TDP1 (0.54) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL20654845 | 0.75 | TDP1 (0.51) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL16382562 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL24383850 | 0.75 | KDM4E (0.51) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL21290253 | 0.74 | JMJD6 (0.51) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL18760785 | 0.74 | TDP1 (0.56) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL19928034 | 0.74 | MAPT (0.57) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | HDAC7, ACHE, BRDT | ALDH1A1 865/4885KMT2A 342/4885TDP1 3193/4885 |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | C3AR1, C5, C9 | ALDH1A1 3404/4885KMT2A 2752/4885TDP1 4037/4885 |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | ALDH1A1 3404/4885KMT2A 2752/4885TDP1 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.