Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19825215 | 0.90 | KMT2A (0.39) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL9935809 | 0.85 | ALDH1A1 (0.63) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| Formic Acid SCHEMBL28843265 | 0.84 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL4361611 | 0.83 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL6115033 | 0.83 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL1049122 | 0.83 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL19824999 | 0.83 | TLR8 (0.37) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| Bromide SCHEMBL4479559 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| SCHEMBL2397143 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2ATLR8AGTR1 | |
| Water SCHEMBL28178859 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2ATLR8AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3275878-B1 | CYCLIC AMINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES (JP) | 2020-05-20 | — | — | EP | disclosed |