SCHEMBL22005651

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20154227	0.85	TDP1 (0.50)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3
	SCHEMBL20154215	0.85	ALDH1A1 (0.47)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3
	SCHEMBL22920673	0.79	TDP1 (0.57)	ALDH1A1KMT2ATDP1MAPTLMNA
	SCHEMBL21037483	0.78	ALDH1A1 (0.52)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3
	SCHEMBL20154164	0.78	ALDH1A1 (0.52)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3
	SCHEMBL20654844	0.77	TDP1 (0.50)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3
	SCHEMBL16382562	0.77	ALDH1A1 (0.53)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3
	SCHEMBL14822692	0.77	TDP1 (0.50)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3
	SCHEMBL22005632	0.75	TDP1 (0.53)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3
	SCHEMBL21290242	0.75	TDP1 (0.49)	ALDH1A1KMT2ATDP1SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.