Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21727223 | 0.94 | SCN5A (0.51) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL18568496 | 0.92 | HRH3 (0.52) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL5911217 | 0.89 | HRH3 (0.62) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL4381194 | 0.87 | HRH3 (0.59) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL5910693 | 0.87 | HRH3 (0.57) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL13661585 | 0.85 | HRH3 (0.56) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL17526233 | 0.84 | HRH3 (0.55) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL17526224 | 0.84 | HRH3 (0.55) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL8309175 | 0.83 | HRH3 (0.50) | HRH3SCN5AKDM1ASMN1; SMN2LMNA | |
| SCHEMBL739192 | 0.82 | HRH3 (0.65) | HRH3SMN1; SMN2CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135672-B9 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC (US) | 2020-05-20 | — | — | EP | disclosed |