Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526224 | 0.97 | HRH3 (0.55) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL5911217 | 0.97 | HRH3 (0.62) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL5910693 | 0.95 | HRH3 (0.57) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL13661585 | 0.93 | HRH3 (0.56) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL17526233 | 0.92 | HRH3 (0.55) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL8307200 | 0.89 | ACE2 (0.61) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL29254420 | 0.87 | HRH3 (0.62) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL18024053 | 0.87 | HRH3 (0.50) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL22005759 | 0.87 | HRH3 (0.50) | HRH3SCN5AKDM1ACARM1PRMT6 | |
| SCHEMBL6510779 | 0.87 | ACE2 (0.54) | HRH3SCN5AKDM1ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | HRH3 452/4885SCN5A 3513/4885KDM1A 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.