Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22006228 | 0.83 | CA12 (0.46) | MAOBMAOAPTGDR2ALDH1A1ALOX15 | |
| SCHEMBL7514414 | 0.81 | RARB (0.40) | MAOBMAOAALDH1A1ALOX15RXRA | |
| SCHEMBL667823 | 0.81 | ALDH1A1 (0.47) | MAOBMAOAALDH1A1ALOX15RXRA | |
| SCHEMBL7735953 | 0.78 | RARB (0.46) | MAOBMAOAALDH1A1ALOX15LMNA | |
| SCHEMBL14728203 | 0.77 | ALDH1A1 (0.47) | MAOBMAOAALDH1A1ALOX15RXRA | |
| SCHEMBL16066498 | 0.77 | ALDH1A1 (0.47) | MAOBMAOAALDH1A1ALOX15RXRA | |
| SCHEMBL17478735 | 0.75 | MRGPRX4 (0.57) | MAOBMAOAPTGDR2RXRARXRB | |
| SCHEMBL4799836 | 0.74 | MAOB (0.49) | MAOBMAOAPTGDR2ALDH1A1LMNA | |
| SCHEMBL1555099 | 0.74 | CPS1 (0.61) | ALDH1A1ALOX15LMNAHPGDMAPK1 | |
| SCHEMBL17478646 | 0.73 | HPGD (0.49) | MAOBMAOAPTGDR2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157122-A1 | BORON-CONTAINING DIACYLHYDRAZINES | CD22, BRDT, BCR | MAOB 2947/4885MAOA 4677/4885PTGDR2 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.