SCHEMBL22006356

SCHEMBL22006356

O=c1[nH]c(=O)c2oc3cccc(Cl)c3c2[nH]1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 5/20 0.41
CSNK2A2 P19784 5/20 0.41
CSNK2B P67870 5/20 0.41
PIM3 Q86V86 5/20 0.41
PIM2 Q9P1W9 5/20 0.41
PSMB8 P28062 1/20 0.40
PARP1 P09874 2/20 0.36
CHEK1 O14757 1/20 0.35
DAO P14920 2/20 0.35
AHR P35869 1/20 0.35
TTR P02766 2/20 0.35
PBRM1 Q86U86 1/20 0.35
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22006833 0.77 AHR (0.42) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL1309845 0.75 ERCC5 (0.54) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL16835579 0.71 GABRP (0.47) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL22006946 0.70 DAO (0.46) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL2497885 0.70 PIM1 (0.54) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL3110872 0.68 CHEK1 (0.55) PARP1CHEK1DAOPBRM1CA12
SCHEMBL2922284 0.68 DAO (0.60) PIM1PARP1CHEK1DAOCA12
SCHEMBL29734052 0.68 CHEK1 (0.55) PARP1CHEK1DAOPBRM1CA12
SCHEMBL7027217 0.67 HTT (0.42) PARP1CHEK1DAOCA12CA9
Potassium SCHEMBL3642930 0.67 CHEK1 (0.54) PARP1CHEK1DAOPBRM1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200161564-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200161564-A1 ORGANIC COMPOUND, COMPOSITION, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OXER1, OR10J3, OCIAD1 PIM1 4316/4885CSNK2A2 880/4885CSNK2B 1076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.