SCHEMBL2200758

SCHEMBL2200758

CCOC(=O)c1ccc(-c2ccccc2)c(C(=O)OCC)c1C(=O)OCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
ALDH1A1 P00352 9/20 0.54
HPGD P15428 6/20 0.54
SMN1; SMN2 Q16637 6/20 0.54
MAPT P10636 6/20 0.54
GAA P10253 5/20 0.54
RAB9A P51151 4/20 0.54
KDM4E B2RXH2 3/20 0.54
NPC1 O15118 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
LMNA P02545 2/20 0.54
MEN1 O00255 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
KMT2A Q03164 1/20 0.53
ADORA3 P0DMS8 2/20 0.50
NFKB1 P19838 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30488962 1.00 TSHR (0.56) TSHRALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL27984025 0.88 TSHR (0.53) TSHRALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL3869093 0.88 TSHR (0.61) TSHRALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL30488959 0.85 TSHR (0.60) TSHRALDH1A1SMN1; SMN2KDM4ELMNA
SCHEMBL2203499 0.85 TSHR (0.60) TSHRALDH1A1SMN1; SMN2KDM4ELMNA
SCHEMBL28998463 0.84 ALDH1A1 (0.54) TSHRALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL30681198 0.84 TSHR (0.49) TSHRALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL18803865 0.83 ALDH1A1 (0.59) TSHRALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL4578589 0.83 TSHR (0.47) TSHRALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL28161602 0.83 TSHR (0.65) TSHRALDH1A1HPGDSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456289-B Titanium-containing catalyst, catalyst for olefin polymerization, preparation method and application thereof 中国石油化工股份有限公司 2024-02-13 CN claimed
CN-114456289-B Titanium-containing catalyst, catalyst for olefin polymerization, preparation method and application thereof 中国石油化工股份有限公司 2024-02-13 CN disclosed
CN-114456288-B Titanium-containing catalyst, catalyst for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-02-13 CN disclosed
EP-2345675-B1 A CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE PETROCHINA CO LTD (CN) 2017-11-08 EP disclosed
US-8470941-B2 Catalyst for homopolymerizing and copolymerizing propylene and its preparation and use PETROCHINA COMPANY LIMITED (CN) 2013-06-25 US disclosed
US-20110207900-A1 CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE PETROCHINA COMPANY LIMITED (CN) 2011-08-25 US disclosed
EP-2345675-A1 A CATALYST FOR HOMOPOLYMERIZING AND COPOLYMERIZING PROPYLENE AND ITS PREPARATION AND USE Petrochina Company Limited (CN) 2011-07-20 EP disclosed