SCHEMBL3869093

SCHEMBL3869093

CCOC(=O)c1cccc(-c2ccccc2)c1C(=O)OCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
ALDH1A1 P00352 8/20 0.54
MAPT P10636 7/20 0.54
HPGD P15428 5/20 0.54
GAA P10253 5/20 0.54
RAB9A P51151 4/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
KDM4E B2RXH2 3/20 0.54
NPC1 O15118 3/20 0.54
LMNA P02545 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
MEN1 O00255 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP2D6 P10635 1/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5572324 0.92 PTPN1 (0.55) TSHRALDH1A1MAPTHPGDGAA
SCHEMBL18803865 0.90 ALDH1A1 (0.59) TSHRALDH1A1MAPTHPGDGAA
SCHEMBL31121002 0.88 PTPN1 (0.54) TSHRALDH1A1MAPTHPGDGAA
SCHEMBL28754871 0.88 ALDH1A1 (0.63) TSHRALDH1A1KDM4ELMNACYP3A4
SCHEMBL30488962 0.88 TSHR (0.56) TSHRALDH1A1MAPTHPGDGAA
SCHEMBL2200758 0.88 TSHR (0.56) TSHRALDH1A1MAPTHPGDGAA
SCHEMBL396552 0.87 TSHR (0.69) TSHRALDH1A1MAPTHPGDGAA
SCHEMBL23689805 0.86 TSHR (0.62) TSHRALDH1A1MAPTHPGDGAA
SCHEMBL27636759 0.86 ALDH1A1 (0.55) TSHRALDH1A1MAPTHPGDGAA
SCHEMBL27364778 0.85 TSHR (0.65) TSHRALDH1A1MAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573956-A Preparation method of nano magnesium hydroxide modified degradable copolyester 浙江恒逸石化研究院有限公司 2022-06-03 CN claimed
CN-102807560-A New method for synthesizing esomeprazole through asymmetrically catalytic oxidation Shouguang fukang pharmaceutical co ltd 2012-12-05 CN claimed
CN-102731758-A Foamable flame-retarding polyester capable of being used for supercritical CO2 and preparation method and application thereof Lanhai yongle jiangsu new material co ltd 2012-10-17 CN claimed
CN-102492124-A Alcohol in-situ modified high melt strength polyester capable of being used for carbon dioxide foaming, and preparation method and application thereof UNIV EAST CHINA SCIENCE & TECH 2012-06-13 CN claimed
CN-102492123-A Method for preparing polyester with high melt strength for foaming CO2 by polyprotic acid in-situ modification and application thereof UNIV EAST CHINA SCIENCE & TECH 2012-06-13 CN claimed
CN-114573956-A Preparation method of nano magnesium hydroxide modified degradable copolyester 浙江恒逸石化研究院有限公司 2022-06-03 CN disclosed
CN-112500569-B Polyimide precursor composition, polyimide film, laminated film, and display device 武汉柔显科技股份有限公司 2021-05-25 CN disclosed
CN-112500569-A Polyimide precursor composition, polyimide film, laminated film, and display device 武汉柔显科技股份有限公司 2021-03-16 CN disclosed
CN-102344517-B Polymer microballoons and preparation method thereof YANG CHENGLI 2015-04-01 CN disclosed
US-8976437-B2 Transflective electrochromic liquid crystal display device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-03-10 US disclosed
CN-102603929-B Preparation method of polymer particles WUXI KNOWLEDGE & BENEFIT SPHERE TECH. CO., LTD. (CN) 2014-10-29 CN disclosed
US-20130222748-A1 TRANSFLECTIVE ELECTROCHROMIC LIQUID CRYSTAL DISPLAY DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2013-08-29 US disclosed
CN-102807560-A New method for synthesizing esomeprazole through asymmetrically catalytic oxidation Shouguang fukang pharmaceutical co ltd 2012-12-05 CN disclosed
CN-102731758-A Foamable flame-retarding polyester capable of being used for supercritical CO2 and preparation method and application thereof Lanhai yongle jiangsu new material co ltd 2012-10-17 CN disclosed
CN-102603929-A Preparation method of polymer particles WUXI KNOWLEDGE & BENEFIT SPHERE TECH CO LTD 2012-07-25 CN disclosed
CN-102492124-A Alcohol in-situ modified high melt strength polyester capable of being used for carbon dioxide foaming, and preparation method and application thereof UNIV EAST CHINA SCIENCE & TECH 2012-06-13 CN disclosed
CN-102492123-A Method for preparing polyester with high melt strength for foaming CO2 by polyprotic acid in-situ modification and application thereof UNIV EAST CHINA SCIENCE & TECH 2012-06-13 CN disclosed
CN-102344517-A Polymer microballoons and preparation method thereof CHENGLI YANG 2012-02-08 CN disclosed
JP-2009042697-A ELECTROCHROMIC ELEMENT MURAKAMI CORP 2009-02-26 JP disclosed