Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 17/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 17/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 17/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 16/20 | 0.34 |
| ▸ | TSHR | P16473 | 15/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | USP2 | O75604 | 6/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | LMNA | P02545 | 8/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22008945 | 0.78 | GPR119 (0.33) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL24651143 | 0.68 | CYP1A2 (0.46) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL22010140 | 0.67 | PDE9A (0.42) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL24651144 | 0.67 | NPC1 (0.43) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL23217165 | 0.66 | EGFR (0.43) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL29844225 | 0.66 | EGFR (0.43) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL27217791 | 0.66 | NPC1 (0.42) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL25647777 | 0.65 | MAPT (0.38) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL31125830 | 0.65 | MAPT (0.38) | NPC1PKMRAB9ACYP1A2CYP3A4 | |
| SCHEMBL24096641 | 0.65 | TP53 (0.41) | NPC1PKMRAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653626-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-05-20 | — | — | EP | disclosed |