Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25928572 | 0.89 | SYK (0.40) | CRHBPCRHR2ADORA1ADORA2AMEN1 | |
| SCHEMBL901737 | 0.80 | CRHBP (0.50) | CRHBPCRHR2ADORA1ADORA2AMEN1 | |
| SCHEMBL14975399 | 0.75 | ADORA2A (0.59) | CRHBPCRHR2ADORA1ADORA2AMEN1 | |
| SCHEMBL17878908 | 0.74 | SYK (0.45) | ADORA1ADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL29435146 | 0.72 | MCL1 (0.53) | CRHBPCRHR2ADORA1ADORA2AMEN1 | |
| SCHEMBL11921491 | 0.72 | MCL1 (0.53) | CRHBPCRHR2ADORA1ADORA2AMEN1 | |
| SCHEMBL18192034 | 0.71 | MCL1 (0.56) | ADORA1ADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL18192018 | 0.71 | MCL1 (0.56) | ADORA1ADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL24156080 | 0.70 | CRHBP (0.38) | CRHBPCRHR2ADORA1ADORA2AMEN1 | |
| SCHEMBL9007691 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220006018-A1 | COMPOUNDS THAT CAN BE USED FOR PRODUCING AN ORGANIC ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2022-01-06 | — | — | US | disclosed |
| WO-2020099349-A1 | COMPOUNDS THAT CAN BE USED FOR PRODUCING AN ORGANIC ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220006018-A1 | COMPOUNDS THAT CAN BE USED FOR PRODUCING AN ORGANIC ELECTRONIC DEVICE | EED, ICMT, DDT | CRHBP 4665/4885CRHR2 4721/4885ADORA1 3683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.