Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27113744 | 0.95 | RORC (0.36) | EPHX2NR1H4NPC1POLBRAB9A | |
| SCHEMBL27113497 | 0.82 | EPHX2 (0.41) | EPHX2NR1H4RAB9ACA1CA2 | |
| Hydrochloric Acid SCHEMBL7416932 | 0.81 | CYP2C9 (0.54) | EPHX2NR1H4NPC1RAB9ACA1 | |
| SCHEMBL27113742 | 0.81 | SYK (0.40) | EPHX2NR1H4ALDH1A1 | |
| SCHEMBL3672272 | 0.81 | CYP2C9 (0.48) | POLBCA1CA2CYP2C9CYP2C19 | |
| SCHEMBL23135392 | 0.80 | ADRA2A (0.41) | NPC1POLBRAB9ASMN1; SMN2CA1 | |
| SCHEMBL11981491 | 0.80 | IDO1 (0.52) | POLBRAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL11954 | 0.79 | EPHX2 (0.59) | EPHX2NR1H4NPC1RAB9ACA1 | |
| SCHEMBL14524510 | 0.78 | NPC1 (0.44) | NPC1POLBRAB9ASMN1; SMN2CYP2C9 | |
| SCHEMBL27113808 | 0.78 | HTT (0.39) | EPHX2NR1H4RAB9ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | NGLY1, GLMN, GMPS | EPHX2 3509/4885NR1H4 2684/4885NPC1 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.